a Record control number A1997XP47000011

a ISSN 1078-0297

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number QV 4

b Item number .M58 1997

a Personal name Mehmetcik, G.

h Medium Electronic Document

a Title Mitochondrial lipid peroxides and antioxidant enzymes in the liver following phorone-induced glutathione depletion .

c Statement of responsibility, etc Nilgün Alptekin, Güldal Mehmetçik, Müjdat Uysal, Gülçin Aykaç-Toker.

c Date of publication, distribution, etc 1997.

b Name of publisher, distributor, etc PJD Pub.,

a Place of publication, distribution, etc New York :

a Summary, etc The levels of lipid peroxidation product (malondialdehyde = MDA) vitamin C and the activities of glutathione peroxidase (GSH-Px) dismutase (SOD) were determined in the liver and its mitochondrial fraction, in the rats 2 and 18 hr after the injection of phorone, a glutathione (GSH) depleting agent. GSH levels decreased in liver homogenate and its mitochondrial fraction after 2 hr of phorone treatment, but these values returned to normal levels at 18 hr. In GSH depleted conditions, hepatic vitamin C levels increased, GSH-Px and SOD activities remained unchanged in mitochondrial and post-mitochondrial fractions. These results indicate that GSH depletion per se does not influence lipid peroxidation and GSH-Px and SOD activities in the liver and the mitochondrial fraction.

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Pharmacology

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Pathology

a Topical term or geographic name as entry element Rat-Liver

g Relationship information JUN 1997, Vol 96 Issue 3, p353-356

t Title Research Communications In Molecular Pathology And Pharmacology

x International Standard Serial Number 10780297