Expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in healthy and pathologic placentas of human and rat (Kayıt no. 241350)
[ düz görünüm ]
| 000 -LEADER | |
|---|---|
| fixed length control field | naa a22 7ar4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20150602111541.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150427t xxu||||| |||| 00| 0 tu d |
| 001 - CONTROL NUMBER | |
| control field | 264657 |
| 016 ## - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER | |
| Record control number | WOS:000347362000012 |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0065-1281 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NEU |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 050 04 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QU 300 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 573005 |
| Personal name | Acar, Nuray. |
| 245 10 - TITLE STATEMENT | |
| Title | Expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in healthy and pathologic placentas of human and rat |
| Statement of responsibility, etc. | Nuray Acar, Hakan Soylu, Imren Edizer, Ozlem Ozbey, Hakan Er, Gokhan Akkoyunlu, Burcu Gemici, Ismail Ustunel. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Elsevier , |
| Date of publication, distribution, etc. | 2014. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | A relationship has been shown between preeclampsia (PE) and intrauterine growth restriction (IUGR) and oxidative stress (OS). Since such pregnancies experience OS, we aimed to detect the distribution pattern and expression levels of a transcription factor, Nuclear factor erythroid 2-related factor-2 (Nrf2) that has a role in the regulation of antioxidant enzymes, and peroxiredoxin 6 (Prdx6) an antioxidant enzyme, in human healthy, IUGR, PE and in groups of rat healthy and IUGR placentas using immunohistochemistry and Western blotting. Both Nrf2 and Prdx6 immunoreactivities were weaker in human and rat IUGR group placentas compared to human and rat control group placentas, respectively. Nrf2 and Prdx6 were immunostained in labyrinth trophoblasts, decidua, giant, glycogen and fetal vessel endothelial cells in rat control and IUGR group placentas. Nrf2 and Prdx6 immunoreactivities were seen in the decidua, syncytiotrophoblasts, villous stromal cells, and vascular endothelium in human control, IUGR and PE group placentas. Results of Nrf2 and Prdx6 Western blotting applied for rat and human placentas were compatible with the results of Nrf2 and Prdx6 immunohistochemical observations with regard to rat and human placentas. Down-regulation of Nrf2 and Prdx6 proteins in human and rat IUGR group placentas may have led to the formation of OS which may have impaired proliferation and invasion of cytotrophoblasts. (C) 2014 Elsevier GmbH. All rights reserved. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 573143 |
| Topical term or geographic name entry element | Cell Biology |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 572720 |
| Topical term or geographic name entry element | Near East University Article |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 572723 |
| Topical term or geographic name entry element | Yakın Doğu Üniversitesi Makale |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 267746 |
| Topical term or geographic name entry element | Human |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 573277 |
| Topical term or geographic name entry element | IUGR |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 573278 |
| Topical term or geographic name entry element | Nrf2 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 573279 |
| Topical term or geographic name entry element | Intrauterine Growth Restriction |
| 773 ## - HOST ITEM ENTRY | |
| Related parts | 2014 , Vol 116 Issue 8, p1289-1300 |
| International Standard Serial Number | 00651281 |
| Title | Acta Histochemica |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1016/j.acthis.2014.07.012 ">http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1016/j.acthis.2014.07.012 </a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | 1000007 |
| Call number prefix | QU0000300E972014 |
| Koha item type | Online Electronic Document |
| Total checkouts | Full call number | Barcode | Koha item type | Lost status | Damaged status | Not for loan | Withdrawn status | Home library | Current library | Shelving location |
|---|---|---|---|---|---|---|---|---|---|---|
| QU 300 .E97 2014 | EOL-160 | Online Electronic Document | NEU Grand Library | NEU Grand Library | Online electronic |