MARC ayrıntıları
| 000 -LEADER |
|---|
| fixed length control field |
naa a22 7ar4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20151109091556.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
150427t xxu||||| |||| 00| 0 tu d |
| 001 - CONTROL NUMBER |
|---|
| control field |
265994 |
| 016 ## - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER |
|---|
| Record control number |
000240458000008 |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
|---|
| International Standard Serial Number |
1612-1872 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
NEU |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 050 04 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QD31.2 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
573443 |
| Personal name |
Çalış, İhsan, |
| Titles and words associated with a name |
Prof. Dr. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Antitrypanosomal cycloartane glycosides from Astragalus baibutensis |
| Statement of responsibility, etc. |
Ihsan Calis, Semra Koyunoglu, Akgul Yesilada, Reto Brun, Peter Rueedi, Deniz Tasdemir. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Date of publication, distribution, etc. |
2006. |
| Name of publisher, distributor, etc. |
Wiley-V C H Verlag Gmbh, |
| Place of publication, distribution, etc. |
Weinheim : |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Baibutoside (5), a new cycloartane-type triterpene glycoside, has been isolated from the roots of Astragalus baibutensis along with four known glycosides, acetylastragaloside 1 (1), and astragalosides 1, 11, and IV (2-4, resp.). The structure elucidation of the compounds were achieved by a combination of one- and two-dimensional NMR techniques (DQF-COSY, HSQC, HMBC, and ROESY), and mass spectrometry (ESI-MS), where all the compounds were shown to have cycloastragenol (=(20R,24S)-3 beta,6 alpha,16 beta,25-tetrahydroxy-20,24-epoxy-9,19-cyclolanostane) as aglycone. All compounds were tested for in vitro antiprotozoal activity. Compounds 1-4 displayed notable activity vs. Trypanosoma brucei rhodesiense, with acetylastragaloside 1 (1) being the most potent (IC50 9.5 mu g/ml). Acetylastragaloside I (1) was also lethal to T cruzi (IC50 5.0 mu g/ml), and it is the first cycloartane-type triterpene with remarkable trypanocidal activity against both T brucei rhodesiense and T cruzi. However, it exhibits some cytotoxicity on mammalian cells. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
118251 |
| Topical term or geographic name entry element |
Chemistry |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
572720 |
| Topical term or geographic name entry element |
Near East University Article |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
572723 |
| Topical term or geographic name entry element |
Yakın Doğu Üniversitesi Makale |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
574781 |
| Topical term or geographic name entry element |
Biochemistry & Molecular Biology |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
574841 |
| Topical term or geographic name entry element |
Triterpene Glycosides |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
574842 |
| Topical term or geographic name entry element |
Lymphocyte-Proliferation |
| 773 ## - HOST ITEM ENTRY |
|---|
| Related parts |
2006, Vol 3 Issue 8, p923-929 |
| Title |
Chemistry & Biodiversity |
| International Standard Serial Number |
16121872 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1002/cbdv.200690094 ">http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1002/cbdv.200690094 </a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| -- |
1000007 |
| Call number prefix |
QD00000312A582006 |
| Koha item type |
Online Electronic Document |
