Comparing subcutaneous and sublingual immunotherapy: what do we know? (Kayıt no. 243133)
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| 000 -LEADER | |
|---|---|
| fixed length control field | naa a22 7ar4500 |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1528-4050 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NEU |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 050 04 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | WD300 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150528t xxu||||| |||| 00| 0 tu d |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 574743 |
| Personal name | Bahceciler, Nerin Nadir |
| 245 10 - TITLE STATEMENT | |
| Title | Comparing subcutaneous and sublingual immunotherapy: what do we know? |
| Statement of responsibility, etc. | Nerin Nadir Bahceciler, Nilufer Galip. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Lippincott Williams & Wilkins |
| Date of publication, distribution, etc. | 2012. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Purpose of review <br/><br/>Although allergen-specific sublingual (SLIT) and subcutaneous immunotherapy (SCIT) have been demonstrated to be clinically effective with similar immunological responses, head-to-head studies comparing those two modes of allergen administration in terms of onset of clinical improvement along with simultaneous immunological responses and underlying mechanisms of preventive effect are scarce. The present review will update current data on this issue. <br/><br/>Recent findings <br/><br/>Compared with SLIT, SCIT provides a rapid onset of clinical improvement by eliciting a simultaneous surge in production of T helper 1 (Th1) and T regulatory cell (Treg) cytokines and blocking antibodies. Similar immunological and clinical responses are evoked quite later, with no effect on Immunoglobulin G (IgG)4 levels during SLIT. Increases in TGF beta secretion due to nonrelevant allergens during SLIT may explain the preventive effect on new sensitizations. <br/><br/>Summary <br/><br/>SLIT and SCIT are both clinically effective in the treatment of respiratory allergic diseases with slight differences in the early phase in terms of onset of clinical efficacy and simultaneous immunological responses. Both SLIT and SCIT induce similar T-cell responses in time, but specific IgG4-blocking antibody responses are more prevalent following SCIT. Further head-to-head studies addressing the preventive effect of monotherapy and the efficacy and immunological responses of nonrelated multiallergen immunotherapy in polysensitized patients are warranted. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 572720 |
| Topical term or geographic name entry element | Near East University Article |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 572723 |
| Topical term or geographic name entry element | Yakın Doğu Üniversitesi Makale |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 121939 |
| Topical term or geographic name entry element | Immunology |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 116735 |
| Topical term or geographic name entry element | Allergy |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 574746 |
| Topical term or geographic name entry element | Allergic rhinitis |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 117278 |
| Topical term or geographic name entry element | Asthma |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 573680 |
| Topical term or geographic name entry element | Sublingual immunotherapy |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 574747 |
| Topical term or geographic name entry element | Grass-Pollen Extract |
| 773 ## - HOST ITEM ENTRY | |
| Related parts | DEC 2012,Vol 12, Issue 6, p640-647 |
| Title | Current Opinion In Allergy And Clinical Immunology |
| International Standard Serial Number | 1528-4050 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1097/ACI.0b013e328358d5f2 ">http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1097/ACI.0b013e328358d5f2 </a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | 1000007 |
| Call number prefix | WD0000300C662012 |
| Koha item type | Online Electronic Document |
| Total checkouts | Full call number | Barcode | Koha item type | Lost status | Damaged status | Not for loan | Withdrawn status | Home library | Current library | Shelving location |
|---|---|---|---|---|---|---|---|---|---|---|
| WD300 .C66 2012 | EOL-1368 | Online Electronic Document | NEU Grand Library | NEU Grand Library | Online electronic |