Clinical course of primary focal segmental glomerulosclerosis (FSGS) in Turkish children: a report from the Turkish Pediatric Nephrology FSGS Study Group. (Kayıt no. 243866)
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| fixed length control field | naa a22 7ar4500 |
| 016 ## - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER | |
| Record control number | 000281020000004 |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 00414301 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NEU |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 050 04 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | WJ 301 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160411133210.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150313t xxu||||| |||| 00| 0 tu d |
| 001 - CONTROL NUMBER | |
| control field | 267199 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 576308 |
| Personal name | Besbas, N. |
| 245 10 - TITLE STATEMENT | |
| Title | Clinical course of primary focal segmental glomerulosclerosis (FSGS) in Turkish children: a report from the Turkish Pediatric Nephrology FSGS Study Group. |
| Statement of responsibility, etc. | Nesrin Besbas, Fatih Ozaltin, Sevinc Emre et al. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2010. |
| Name of publisher, distributor, etc. | Turkish J Pediatrics, |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The clinical course of focal segmental glomerulosclerosis (FSGS) is heterogeneous in children. To evaluate the clinical course and the predictors of outcome in Turkish children with primary FSGS, a retrospective study was conducted by the Turkish Pediatric Nephrology Study Group in 14 pediatric nephrology centers. Two hundred twenty-two patients (92 boys, 130 girls, aged 1-16 years) with biopsy-proven primary FSGS were included. One hundred forty-eight patients were followed-up for a median of 51 months (range: 0.26-270). The clinical course was characterized by complete remission in 50 (33.8%), persistent proteinuria in 50 (33.8%) and progression to renal failure in 48 (32.4%) patients. Progression to end-stage renal disease (ESRD) was significantly higher in patients who did not attain remission. Complete remission, partial remission and progress to renal failure were recorded in 37%, 32% and 28%, respectively, of the patients (n=73) treated with prednisone combined cyclophosphamide/cyclosporine A. However, in patients (n=33) treated with pulse methyl prednisolone plus oral prednisone (up to 20 months) combined with cyclophosphamide, complete remission in 51.5% and partial remission in 27.3% of the patients were noted. Progression to renal failure was observed in 9.1% of this group of patients. Multivariate analysis showed that only plasma creatinine at presentation was an independent predictive value for outcome. Patients with serum creatinine level higher than 1.5 mg/dl had 6.6 times increased rate of progression to renal failure. Failure to achieve remission is a predictor of renal failure in children with primary FSGS. The use of immunosuppressive treatment in conjunction with prolonged steroid seems beneficial in primary FSGS in children. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 576309 |
| Topical term or geographic name entry element | Kidney |
| General subdivision | Disease |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 572720 |
| Topical term or geographic name entry element | Near East University Article |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 572723 |
| Topical term or geographic name entry element | Yakın Doğu Üniversitesi Makale |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 118290 |
| Topical term or geographic name entry element | Children |
| 773 ## - HOST ITEM ENTRY | |
| Main entry heading | Turkish Journal Of Pediatrics |
| Related parts | MAY-JUN, 2010, 52 3, p255-p261, 7p. |
| International Standard Serial Number | 00414301 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | 1000007 |
| Call number prefix | WJ0000301C552010 |
| Koha item type | Online Electronic Document |
| Total checkouts | Full call number | Barcode | Koha item type | Lost status | Damaged status | Not for loan | Withdrawn status | Home library | Current library | Shelving location |
|---|---|---|---|---|---|---|---|---|---|---|
| WJ 301 .C55 2010 | EOL-1479 | Online Electronic Document | NEU Grand Library | NEU Grand Library | Online electronic |